Diem was first diagnosed with ovarian cancer when she was 23. She went into remission but the disease returned in 2012.
She lost both ovaries but not before doctors were able to freeze some of her eggs to allow her to have a biological child in the future.
She went into remission for a second time in 2013 following several months of treatment.
But this summer she suffered another devastating blow after learning the cancer had returned, this time to her colon and stomach.
Doctors had to perform an emergency hysterectomy in August, dashing her hopes of carrying a child.
In October, doctors told her that the stomach and colon cancer they had found in August had spread to her liver and lymph nodes.
Diem Brown's sad passing was first reported by People. MTV released a statement via US Weekly soon after;
MTV is tremendously sad to hear the news that Diem Brown has lost her long battle with cancer. We send our deepest condolences to her family and friends. Diem was a true fighter and brought passion to everything she touched. We will miss her.'
Her fans, former co-stars, and others she had touched with her activism have been posting their condolences online using the hashtag #RIPDiemBrown
Read more: MailOnline
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